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Memorias do Instituto Oswaldo Cruz
Article . 2011 . Peer-reviewed
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Memorias do Instituto Oswaldo Cruz
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Genetic diversity of noroviruses in Brazil

Authors: Fioretti, Julia Monassa; Ferreira, Mônica Simões Rocha; Victoria, Matias; Vieira, Carmen Baur; Xavier, Maria da Penha Trindade Pinheiro; Leite, José Paulo Gagliardi; Miagostovich, Marize Pereira;

Genetic diversity of noroviruses in Brazil

Abstract

Norovirus (NoV) infections are a major cause of acute gastroenteritis outbreaks around the world. In Brazil, the surveillance system for acute diarrhoea does not include the diagnosis of NoV, precluding the ability to assess its impact on public health. The present study assessed the circulation of NoV genotypes in different Brazilian states by partial nucleotide sequencing analysis of the genomic region coding for the major capsid viral protein. NoV genogroup II genotype 4 (GII.4) was the prevalent (78%) followed by GII.6, GII.7, GII.12, GII.16 and GII.17, demonstrating the great diversity of NoV genotypes circulating in Brazil. Thus, this paper highlights the importance of a virological surveillance system to detect and characterize emerging strains of NoV and their spreading potential.

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Keywords

Adult, Adolescent, Genotype, Molecular Sequence Data, norovirus, Infectious and parasitic diseases, RC109-216, Microbiology, Feces, Young Adult, genotypes, Humans, Child, Phylogeny, Caliciviridae Infections, Reverse Transcriptase Polymerase Chain Reaction, Norovirus, Genetic Variation, Infant, Sequence Analysis, DNA, Middle Aged, QR1-502, Gastroenteritis, Child, Preschool, RNA, Viral, gastroenteritis, Brazil

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    46
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
46
Top 10%
Top 10%
Top 10%
Green
gold