In order to improve performance while keeping high spectrum efficiency of analog signal transmission, we recently proposed an analog single-carrier transmission with frequency-domain equalization (analog SC-FDE). In this paper, in order to improve the spectrum efficiency, analog SC-FDE using single sideband (SSB) technique is proposed. A theoretical analysis of normalized mean square error (NMSE) performance is carried out and confirmed by computer simulation. We show that analog SC-FDE using SSB technique achieves better NMSE performance than both conventional SSB transmission and analog SC-FDE while doubling spectrum efficiency of analog SC-FDE.