
doi: 10.1586/eri.10.127
pmid: 21133664
The rate of perinatal HIV transmission has decreased significantly in developed countries. However, worldwide, it remains the main source of HIV infection within the pediatric population. Recent advances as a result of findings from clinical trials, viral resistance testing and the advent of new drugs have increased the options for initial treatment regimens. This article provides an overview of antiretroviral therapy in treatment-naive children, including recent pediatric data and updated guidelines from the NIH. It also provides information on new drugs approved for the pediatric age group, dosage information, drug resistance testing and monitoring suggestions for children and adolescents receiving antiretroviral therapy. Special issues pertaining to adherence, disclosure and contraception are also highlighted.
Male, Clinical Trials as Topic, Adolescent, Anti-HIV Agents, Infant, Newborn, HIV Infections, Viral Load, Pregnancy, Antiretroviral Therapy, Highly Active, Child, Preschool, Drug Resistance, Viral, HIV-1, Humans, Female, Pregnancy Complications, Infectious, Child
Male, Clinical Trials as Topic, Adolescent, Anti-HIV Agents, Infant, Newborn, HIV Infections, Viral Load, Pregnancy, Antiretroviral Therapy, Highly Active, Child, Preschool, Drug Resistance, Viral, HIV-1, Humans, Female, Pregnancy Complications, Infectious, Child
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