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Infant Botulism

Authors: A, Glatman-Freedman;

Infant Botulism

Abstract

Infant botulism was first described in 1976. It is caused by Clostridium botulinum, a gram-positive anaerobic bacillus found most commonly in soil and agricultural products. The organism forms spores and during growth and germination releases a potent neurotoxin that is responsible for the illness. Eight neurotoxins have been recognized, but infant botulism is caused primarily by organisms producing toxin types A and B. Although adult-type botulism occurs by ingesting food contaminated with botulinus toxin, infant botulism seems to result from ingestion of spores that germinate and release the toxin inside the infant's colon. The toxin is absorbed from the gastrointestinal tract, travels via the blood stream, and binds irreversibly to peripheral cholinergic nerve synapses, where it prevents the release of acetylcholine.

Related Organizations
Keywords

Male, Age Distribution, Risk Factors, Incidence, Humans, Infant, Botulism, Female, Sex Distribution, Prognosis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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