To the Editor.— Hubert and Toyama1 reported a 2-month-old infant and his mother with hiatal hernia at the age of 2 months and suggested that the condition is transmitted by an autosomal dominant gene. Unlike congenital diaphragmatic hernia, most reviews fail to mention the familial occurrence of gastroesophageal reflux or hiatal hernia. Crabb et al2 described a family in which eight members in three generations had gastroesophageal reflux. In 1984, I reported a 13-month-old girl with gross gastroesophageal reflux.3