To the Editor.— Seizures are a clinical sign that disturbances have or are continuing to occur in the CNS.1 It is important to determine the etiology of a seizure for the purpose of both treating the infant and for predicting later development. Several studies have shown that seizures associated with asphyxia, trauma, infection, and brain anomalies result in fewer normal outcomes than those associated with hypocalcemia, subarachnoid hemorrhage, or even an unknown etiology.2 Experimental evidence suggests that seizures per se have a detrimental effect on the immature brain.