As of April, 1958, there were 124 poison control centers in 40 states and territories. The results of a study of the operations of 102 of these centers are presented. Coordination of activities of poison control centers is desirable, especially where more than one center serve the same area. The American Academy of Pediatrics has led the way in establishing centers all over the country. Increasing numbers of state and local departments of health and medical schools are participating in control of poisonings and strengthening the movement for development of poison control centers. Poison control centers give information concerning toxicity of a variety of products and substances. Many also maintain facilities for treatment of poisoning, but emergency rooms of all hospitals should be equipped to give proper treatment for poisoning. Prevention of accidental poisoning is the best "treatment" for this "disease." Followup studies of patients will uncover significant causal factors and enable effective preventive measures to be instituted. All physicians are encouraged to learn the location and utilize the services of the nearest poison control center.