Climate change leads to increased environmental temperatures, which negatively affects the bodies of animals. Rabbits do not have sweat glands and are not able to regulate their body temperature, which, under conditions of heat stress, disrupts the physiological processes of the body: body thermoregulation, respiration, immune function, endocrine regulation, blood parameters, reproductive capacity, which are critical factors in ensuring the functioning of the body. In recent years, in order to mitigate heat stress, considerable attention has been focused on compounds produced by nanotechnology, which have a positive effect on the animal body compared to organic and inorganic substances and have a wide range of biological effects. However, the effect of macro- and microelement nanoparticles on the mammalian body depends on the amount used. Therefore, the purpose of the experiment was to study the hematological and biochemical parameters of rabbits after weaning under moderate heat stress by feeding Zinc, Selenium and Germanium citrates produced by nanotechnology.