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Revista de Investigaciones Veterinarias del Perú
Article . 2011 . Peer-reviewed
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Revista de Investigaciones Veterinarias del Perú
Article
License: CC BY NC SA
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INTERRUPCIÓN DE GESTACIÓN EN UNA PERRA MEDIANTE UN TRATAMIENTO COMBINADO DE CLOPROSTENOL Y CABERGOLINA

Authors: Sánchez R., Alfonso; Rojas C., Gonzalo; Moreno M., Paloma;

INTERRUPCIÓN DE GESTACIÓN EN UNA PERRA MEDIANTE UN TRATAMIENTO COMBINADO DE CLOPROSTENOL Y CABERGOLINA

Abstract

The effectiveness of a combined treatment of cloprostenol and cabergoline was evaluated for interruption of gestation in bitches. A clinical experience is reported in an English bulldog bitch with a gestation of 30 days. The treatment was administrated every 24 hours and consisted in 5 μg/kg of cabergoline, orally, followed 30 minutes later by 1 μg/kg of cloprostenol, via subcutaneous. Physiological constants, effects post administration, and ecographic evolution of the gestation was evaluated. Also, progesterone concentration was determined in two blood samples using a quantitative commercial kit. Changes in gestational vesicles were observed at day 3 of treatment, and a lower cardiac frequency (<180 bpm) were recorded on day 4. A fetal expulsion occurred few hours later. Ultrasound on day 5 showed absence of vesicles and fetuses. Serum progesterone concentration on day 3 was 1 to 2.5 ng/ml, incompatible with the maintenance of gestation, and on day 5 was <1 ng/ml. The results allowed confirming the effectiveness of this protocol to interrupt gestations in bitches, highlighting the short duration of the treatment (4 days).

Se evaluó la efectividad de un tratamiento combinado de cloprostenol y cabergolina como método de interrupción de la gestación en hembras caninas. Se describe el caso de una perra Bulldog Inglés con gestación estimada de 30 días. Cada 24 horas se aplicó 5 μ/kg de cabergolina, vía oral, seguido a los 30 min de 1μ/kg de cloprostenol, vía subcutánea. Se evaluaron constantes fisiológicas, efectos post administración y evolución ecográfica de la gestación; asimismo, se determinó la concentración de progesterona sérica utilizando un kit comercial cuantitativo. Cambios en las vesículas gestacionales se observaron en el día 3 del tratamiento, y en el día 4 se evidenció una frecuencia cardíaca disminuida (<180 lpm), y una expulsión fetal horas más tarde. El examen ecográfico del día 5 mostró ausencia de vesículas gestacionales y fetos. La progesterona sérica en el día 3 fue de 1 a 2.5 ng/ml, incompatible con la mantención de la gestación y en el día 5 fue de <1 ng/ml. Los resultados permiten confirmar la efectividad del protocolo usado para interrumpir gestaciones en caninos, destacando el corto tiempo del tratamiento (4 días).

Keywords

cloprostenol, Perra, termination of pregnancy, cabergoline, perra, cabergolina, bitch, interrupción de preñez

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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