Part 1 Introduction: Challenges of bone repair Bone anatomy, physiology and adaptation to mechanical loading Bone repair and regeneration Biomechanical aspects of bone repair. Part 2 Biomaterials: Properties and characterisation of bone repair materials Metals as bone repair materials Ceramics as bone repair materials Polymers for bone repair Composite biomaterials for bone repair Cements as bone repair materials Bioactive polymer coatings to improve bone repair Long-term performance and failure of orthopaedic devices. Part 3 Clinical applications: Using bone repair materials in orthopaedic surgery Bone tissue engineering Retrieval and analysis of orthopaedic implants Ethical issues in bone repair and bone tissue engineering.