Identification of somatostatin in the human placenta

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1982Publisher:Oxford University Press (OUP)Journal:Acta Endocrinologica, volume 99, pages 601-604 (issn: 0804-4643, eissn: 1479-683X,

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Authors: J N, Lee; P, Wu; T, Chard;

doi: 10.1530/acta.0.0990601

pmid: 6122323

Identification of somatostatin in the human placenta

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Abstract

Abstract. High pressure liquid chromatography (HPLC), gel chromatography and radioimmunoassay (RIA) were applied to the identification of cyclic somatostatin in human placental tissue. Methanol extracts of the placenta were treated with acetic acid and chloroform, purified on an octadecylsilane column, fractionated on HPLC and gel filtration, and assessed by RIA. It is concluded that human placental somatostatin is similar or identical to cyclic somatostatin on other tissue.

Related Organizations

Queen Mary University of London
United Kingdom

Keywords

Pregnancy, Placenta, Chromatography, Gel, Radioimmunoassay, Humans, Female, Somatostatin, Chromatography, High Pressure Liquid

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