The effect of clomiphene citrate on pubertal gynaecomastia

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1980Publisher:Oxford University Press (OUP)Journal:Acta Endocrinologica, volume 95, pages 177-180 (issn: 0804-4643, eissn: 1479-683X,

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Authors: D, LeRoith; R, Sobel; S M, Glick;

doi: 10.1530/acta.0.0950177

pmid: 6776752

The effect of clomiphene citrate on pubertal gynaecomastia

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Abstract

Abstract. Clomiphene citrate 100 mg daily was used to treat 28 boys with pubertal gynaecomastia. Six failed to complete the course and of the remaining, 14 (64%) responded within 6 months of commencement of therapy. LH, FSH, testosterone and oestradiol levels rose during therapy. It is suggested that clomiphene affects gynaecomastia locally as an anti-oestrogen.

Related Organizations

Ben-Gurion University of the Negev
Israel
Soroka Medical Center
Israel

Keywords

Adult, Male, Adolescent, Estradiol, Puberty, Luteinizing Hormone, Clomiphene, Prolactin, Gynecomastia, Humans, Testosterone, Follicle Stimulating Hormone

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