Anecortave acetate

Sophie J, Bakri; Peter K, Kaiser

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Expert Opinion on Investigational Drugs

Article . 2006 . Peer-reviewed

Data sources: Crossref

Expert Opinion on Investigational Drugs

Article . 2006

Data sources: Europe PubMed Central

Anecortave acetate

descriptionPublicationkeyboard_double_arrow_right Article 24 Jan 2006 English Publisher:Informa HealthcareJournal:Expert Opinion on Investigational Drugs, volume 15, pages 163-169 (issn: 1354-3784, eissn: 1744-7658,

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Authors: Sophie J, Bakri; Peter K, Kaiser;

doi: 10.1517/13543784.15.2.163

pmid: 16433595

Anecortave acetate

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Abstract

This manuscript reviews the pharmacotherapeutics of the novel, angiostatic cortisene, anecortave acetate suspension, for the treatment of age-related macular degeneration. The chemistry, pharmacokinetics and pharmacodynamics of anecortave acetate are discussed, and the results of the multi-centre, randomised, controlled clinical trials for the treatment of subfoveal choroidal neovascularisation in age-related macular degeneration summarised. It also discusses ongoing clinical trials involving anecortave acetate for dry and wet age-related macular degeneration.

Keywords

Macular Degeneration, Animals, Humans, Drugs, Investigational, Pregnadienediols

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