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New Anti-Inflammatory Agents

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2007 English Publisher:Walter de Gruyter GmbHJournal:Zeitschrift für Naturforschung C, volume 62, pages 27-31 (issn: 0939-5075, eissn: 1865-7125,

Authors: Mosaad S. Mohamed; Mostafa Adbel-Monem; Aymn E. Rashad; Samar S. Fatahalla;

doi: 10.1515/znc-2007-1-205

pmid: 17425101

New Anti-Inflammatory Agents

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Abstract

The pyrrole derivatives 1a, b and 2a, b were used as precursors for the preparation of N-substituted pyrrole derivatives 3a, b-9a, b and pyrrolo[2,3-d]pyrimidines 13-16. Also, all the newly prepared products were tested for anti-inflammatory activity as analogues to fenamates, and some of them revealed moderate anti-inflammatory activity compared to the standard drug indomethacin.

Related Organizations

Helwan University
Egypt
National Research Centre
Egypt

Keywords

Models, Molecular, Pyrimidines, Molecular Structure, Anti-Inflammatory Agents, Non-Steroidal, Indomethacin, Animals, Pyrroles, Rats

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	12
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average