
doi: 10.1515/jpm.2011.061
pmid: 21749283
To determine the contribution of twin-to-twin transfusion syndrome (TTTS) to preterm birth (PTB) at <37 weeks of gestation among Japanese twin pregnancies.An observational study using 3241 MC-BA (monochorionic biamniotic) and 6581 BC (bichorionic biamniotic) twin pregnancies. We focused on TTTS, preterm premature rupture of membranes (PPROM), pregnancy-induced hypertension (PIH), and fetal sex as possible causes of PTB.PTB was more common in MC-BA than in BC twin pregnancies (66.9% vs. 57.6%, P<0.0001) whereas PTB after PPROM (8.0% vs. 10.0%) and PIH (5.7% vs. 5.9%) was not. PTB after TTTS occurred in 7.3% of women with MC-BA twins. PTB was significantly more common for male-male pairs than for female-female pairs among both MC-BA (69.2% vs. 64.7%) and BC (59.6% vs. 56.3%) twins.The elevated risk of PTB among MC-BA twins could be explained by the occurrence of TTTS.
Adult, Male, Infant, Newborn, Fetofetal Transfusion, Hypertension, Pregnancy-Induced, Twins, Monozygotic, Sex Factors, Japan, Pregnancy, Risk Factors, Pregnancy, Twin, Twins, Dizygotic, Humans, Premature Birth, Female, Premature Rupture of Fetal Membranes, Infant, Premature
Adult, Male, Infant, Newborn, Fetofetal Transfusion, Hypertension, Pregnancy-Induced, Twins, Monozygotic, Sex Factors, Japan, Pregnancy, Risk Factors, Pregnancy, Twin, Twins, Dizygotic, Humans, Premature Birth, Female, Premature Rupture of Fetal Membranes, Infant, Premature
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