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A Case of Thyrotoxicosis with Pancytopenia.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2001 English Publisher:Japan Endocrine SocietyJournal:Endocrine Journal, volume 48, pages 385-389 (issn: 0918-8959, eissn: 1348-4540,

Authors: Hideji Tanaka; Nobuo Fukuda; Takeshi Soeki; Hisanori Shinohara; Yoshiyuki Tamura; Noriyasu Kondo; Kanji Bando;

doi: 10.1507/endocrj.48.385

pmid: 11523911

A Case of Thyrotoxicosis with Pancytopenia.

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Abstract

We report a 49-year-old man with primary hyperthyroidism who presented with pancytopenia. The patient presented with leg edema, sinus tachycardia, cardiomegaly, and pleural effusions, all from congestive heart failure. Laboratory data showed pancytopenia and primary hyperthyroidism; echocardiogram showed diffuse hyperkinesis of the left ventricular wall and right ventricular overloading. The bone marrow was moderately hypercellular and compatible with arrested hematopoiesis. Pancytopenia and heart failure improved after administration of methimazole and diuretics. However, high levels of thyroid hormone recurred with pancytopenia 4 months after admission. Therefore, subtotal thyroidectomy was performed, and the levels of thyroid hormones and peripheral blood cell counts have remained normal. Pancytopenia may be caused by hyperthyroidism.

Keywords

Heart Failure, Male, Leg, Methimazole, Pancytopenia, Cardiomegaly, Middle Aged, Blood Cell Count, Pleural Effusion, Tachycardia, Sinus, Thyrotoxicosis, Antithyroid Agents, Bone Marrow, Recurrence, Thyroidectomy, Edema, Humans, Diuretics

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	16
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average