Prestressing strands are often located eccentrically within ducts in post-tensioned structures due to curvature of profile. To investigate the bond performance of grouted tendons, pull-out tests are conducted on mono- and multi-strand tendons located eccentrically in grouted ducts in concrete at temperatures of 20°C to 600°C. Each specimen is first heated to the designated temperature and then loaded either immediately or after cooling down. Results show that the bond strength of eccentrically embedded tendons is lower than that of centrally embedded tendons. The bond strength and stiffness are found to decrease with increase of temperature, but the bond recovers certain strength after cooling down. The bond is enhanced by confinement steel surrounding the duct. However, specimens cooled by water behave almost the same as those cooled in air. A bond-slip model is proposed accordingly.