Transformation of the mitochondrial genome

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2013 English Publisher:EHU PressJournal:The International Journal of Developmental Biology, volume 57, pages 659-665 (issn: 0214-6282,

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Authors: Larosa, Véronique; Remacle, Claire;

doi: 10.1387/ijdb.130230cr

pmid: 24166448

handle: 2268/149500

Transformation of the mitochondrial genome

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Abstract

Although mitochondrial transformation is highly desirable in mammals and plants, it is only possible in two unicellular organisms, the budding yeast Saccharomyces cerevisiae and the unicellular green alga Chlamydomonas reinhardtii. Here, we give an overview of the attempts made to transform mitochondria of mammals and plants and the possible reasons for their failure. This review briefly describes the mitochondrial transformation principles in yeast and describes in more detail the transformation and its applications in Chlamydomonas.

Related Organizations

University of Liège
Belgium
Life Sciences Institute
United States

Keywords

DNA, Plant, Sequence Homology, Amino Acid, Molecular Sequence Data, Saccharomyces cerevisiae, Plants, Life sciences, DNA, Mitochondrial, Mitochondria, Biologie végétale (sciences végétales, sylviculture, mycologie...), Genetic Techniques, Genome, Mitochondrial, Mutation, Sciences du vivant, Animals, Humans, Amino Acid Sequence, Transgenes, Genetic Engineering, Phytobiology (plant sciences, forestry, mycology...), Chlamydomonas reinhardtii

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Acetylornithine aminotransferase, mitochondrial
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