
We propose a lightweight data structure for indexing and querying collections of NGS reads data in main memory. The data structure supports the interface proposed in the pioneering work by Philippe et al. for counting and locating $k$-mers in sequencing reads. Our solution, PgSA (pseudogenome suffix array), based on finding overlapping reads, is competitive to the existing algorithms in the space use, query times, or both. The main applications of our index include variant calling, error correction and analysis of reads from RNA-seq experiments.
Genomics (q-bio.GN), FOS: Computer and information sciences, Genome, Sequence Analysis, RNA, Science, Q, R, Datasets as Topic, High-Throughput Nucleotide Sequencing, FOS: Biological sciences, Computer Science - Data Structures and Algorithms, Escherichia coli, Medicine, Animals, Humans, Quantitative Biology - Genomics, Data Structures and Algorithms (cs.DS), Caenorhabditis elegans, Algorithms, Software, Research Article
Genomics (q-bio.GN), FOS: Computer and information sciences, Genome, Sequence Analysis, RNA, Science, Q, R, Datasets as Topic, High-Throughput Nucleotide Sequencing, FOS: Biological sciences, Computer Science - Data Structures and Algorithms, Escherichia coli, Medicine, Animals, Humans, Quantitative Biology - Genomics, Data Structures and Algorithms (cs.DS), Caenorhabditis elegans, Algorithms, Software, Research Article
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 13 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
