Quantitative Analysis of Cell Nucleus Organisation
Copyright policy )Quantitative Analysis of Cell Nucleus Organisation
There are almost 1,300 entries for higher eukaryotes in the Nuclear Protein Database. The proteins' subcellular distribution patterns within interphase nuclei can be complex, ranging from diffuse to punctate or microspeckled, yet they all work together in a coordinated and controlled manner within the three-dimensional confines of the nuclear volume. In this review we describe recent advances in the use of quantitative methods to understand nuclear spatial organisation and discuss some of the practical applications resulting from this work.
- Imperial College London United Kingdom
- City St George’s, University of London United Kingdom
- McGill University Canada
- National Center for Biotechnology Information United States
- United States National Library of Medicine United States
Biochemistry & Molecular Biology, Human-chromosome territories, Bioinformatics, QH301-705.5, Genetic loci, RNA-polymerase-II, Imaging techniques, Review, Models, Biological, Fluorescence imaging, Biochemical Research Methods, Mathematical Sciences, Messenger-RNA, Models, Transcription sites, Interphase nuclei, Biology (General), Quantitative analysis, Cell Nucleus, Spatial-distribution, Science & Technology, Scale chromatin organization, Nuclear Proteins, Genomics, Homologous chromosomes, Biological Sciences, Biological, Chromatin, PML bodies, Mathematical & Computational Biology, Cell nucleus, Life Sciences & Biomedicine, Information And Computing Sciences, Human-lymphocytes, Inactive genes
Biochemistry & Molecular Biology, Human-chromosome territories, Bioinformatics, QH301-705.5, Genetic loci, RNA-polymerase-II, Imaging techniques, Review, Models, Biological, Fluorescence imaging, Biochemical Research Methods, Mathematical Sciences, Messenger-RNA, Models, Transcription sites, Interphase nuclei, Biology (General), Quantitative analysis, Cell Nucleus, Spatial-distribution, Science & Technology, Scale chromatin organization, Nuclear Proteins, Genomics, Homologous chromosomes, Biological Sciences, Biological, Chromatin, PML bodies, Mathematical & Computational Biology, Cell nucleus, Life Sciences & Biomedicine, Information And Computing Sciences, Human-lymphocytes, Inactive genes
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