Ependymal cells SCOre sweet cerebrospinal fluid

descriptionPublicationkeyboard_double_arrow_right Article 22 Sep 2023 English Publisher:Public Library of Science (PLoS)Journal:PLOS Biology, volume 21, page e3002323 (eissn: 1545-7885,

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Authors: Luke L. Liu; Ryann M. Fame;

doi: 10.1371/journal.pbio.3002323

pmid: 37738230

pmc: PMC10516407

Ependymal cells SCOre sweet cerebrospinal fluid

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Abstract

The subcommissural organ (SCO) is a secretory tissue located on the roof of the brain's third ventricle. A new study published in PLOS Biology finds that the SCO responds to glucose by secreting signaling molecules into the cerebrospinal fluid (CSF), thereby decreasing the local ependyma-driven CSF movement.

Related Organizations

Department of Neurosurgery Stanford University
United States
Stanford University
United States

Keywords

Glucose, QH301-705.5, Hyperglycemia, Cell Adhesion Molecules, Neuronal, Humans, Biological Transport, Biology (General), Primer

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