The Institutional Clinical and Translational Science Awards (CTSAs) are the cornerstone of the National Institutes of Health Roadmap Initiative that intends to transform research by promoting new models of research and expanding research training for the future. This initiative is designed to maximize the public’s investment in the biomedical research enterprise through development of new models of clinical research and the training of new types of clinical researchers. Specifically, this model promotes collaboration between disciplines and emphasizes that many of the critical questions in medicine cannot be answered within the confines of single NIH institutes or traditional academic health centers. Additionally, CTSAs should “help deliver improved medical care to the entire population, helping to disseminate new technologies and new advances into clinical practice.”1