Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Optics Lettersarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Optics Letters
Article . 2025 . Peer-reviewed
Data sources: Crossref
Optics Letters
Article . 2025
versions View all 2 versions
addClaim

Adaptive focusing optical coherence tomography for corneal imaging

Authors: Yejiong Shi; Bin He; Zichen Yin; Zhengyu Chen; Zhangwei Hu; Ruizhi Xue; Panqi Yang; +7 Authors

Adaptive focusing optical coherence tomography for corneal imaging

Abstract

Optical coherence tomography (OCT) plays a crucial role in diagnosing corneal diseases due to its capacity to provide high-resolution three-dimensional imaging. However, the convex shape of the cornea and the inherent trade-off between depth of field (DOF) and lateral resolution in OCT systems often result in defocusing issues, leading to reduced lateral resolution and sensitivity in single-shot high-resolution imaging. Traditional methods typically involve multiple focusing at different depths followed by image stitching to achieve full-depth high-resolution imaging of the cornea, which increases imaging times and introduces potential stitching artifacts. To address these limitations, we propose a novel adaptive focusing OCT system. By leveraging the symmetry of the corneal structure and the periodic focusing stability of an electrically tunable lens, our system can achieve full-depth high-resolution imaging of the entire cornea in a single scan, covering an 11 mm imaging range and 1.5 mm depth variation with a lateral resolution of 10 µm. This approach not only halves the imaging time but also eliminates the need for image stitching. Imaging of curved tape samples and excised porcine corneas demonstrates the potential of this novel technique for high-resolution and fast corneal imaging.

Related Organizations
Keywords

Cornea, Swine, Animals, Tomography, Optical Coherence

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Upload OA version
Are you the author of this publication? Upload your Open Access version to Zenodo!
It’s fast and easy, just two clicks!