Continuous health monitoring has become a major theme of our aging society. Portable devices play an important role here. Many optical portable devices are susceptible to motion induced artifacts. We have performed an experimental study for detection of fluid pulsation based on multi-exposure speckle images, in presence of motion induced artifacts. Induced motion of a wide range of frequencies and amplitudes were generated to resemble sensor motion with respect to skin. The data was analyzed using speckle contrast and correlation. We concluded that both techniques have their own advantages, depending on the measurement configuration. A study of angles between illumination and detection revealed that larger angles yields better signal. Shorter exposure time was more successful in extracting the signal. We also performed in-vivo measurements that agree with the in-vitro case. We also show that a minimum collection of two pixels from the speckle image is sufficient to extract relevant results.