Caspofungin
Copyright policy )Caspofungin
Available systemically effective antifungal agents for the treatment of invasive fungal infections are few. With the increasing recognition of a need for newer antifungal drugs, caspofungin has been introduced as the first member of a new class of compounds called echinocandins. This paper reviews the chemistry and mechanism of action of caspofungin, its activity in vitro and in animal models, and clinical pharmacokinetics,clinical efficacy and safety in patients.
- Wayne State University United States
Clinical Trials as Topic, Antifungal Agents, Dose-Response Relationship, Drug, Fungi, Drug Resistance, Microbial, Peptides, Cyclic, Anti-Bacterial Agents, Echinocandins, Lipopeptides, Mycoses, Caspofungin, Animals, Humans, Drug Interactions, Drug Therapy, Combination, Renal Insufficiency, Peptides, Liver Failure
Clinical Trials as Topic, Antifungal Agents, Dose-Response Relationship, Drug, Fungi, Drug Resistance, Microbial, Peptides, Cyclic, Anti-Bacterial Agents, Echinocandins, Lipopeptides, Mycoses, Caspofungin, Animals, Humans, Drug Interactions, Drug Therapy, Combination, Renal Insufficiency, Peptides, Liver Failure
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