RNA Interference for the Treatment of Cancer
Copyright policy )RNA Interference for the Treatment of Cancer
RNA interference (RNAi) is the latest new technology in the field of genetic medicine in which specific genes can be turned off, or silenced, so as to affect a therapeutic outcome. It can be highly specific, works in the nanomolar range and is far more effective than the antisense approaches popular 10-15 years ago. Here we review the field and explore the potential role of RNAi in cancer therapy, highlighting recent progress and examining the hurdles that must be overcome before this promising technology is ready for clinical use.
- University of Queensland Australia
- University of Queensland Australia
- Princess Alexandra Hospital Australia
Prostate-cancer, Carcinoma-cells, Selective Delivery, 321015 Oncology and Carcinogenesis, Cationic Liposomes, Inhibits Tumor-growth, In-vivo, Mammalian-cells, Neoplasms, Double-stranded-rna, Animals, Humans, Pharmacology & Pharmacy, RNA, Messenger, RNA, Small Interfering, Clinical Trials as Topic, Gene Transfer Techniques, Genetic Therapy, 730108 Cancer and related disorders, Human-papillomavirus, Combined Modality Therapy, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Messenger-rna, Liposomes, Mutation, Nanoparticles, RNA Interference, CX, 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
Prostate-cancer, Carcinoma-cells, Selective Delivery, 321015 Oncology and Carcinogenesis, Cationic Liposomes, Inhibits Tumor-growth, In-vivo, Mammalian-cells, Neoplasms, Double-stranded-rna, Animals, Humans, Pharmacology & Pharmacy, RNA, Messenger, RNA, Small Interfering, Clinical Trials as Topic, Gene Transfer Techniques, Genetic Therapy, 730108 Cancer and related disorders, Human-papillomavirus, Combined Modality Therapy, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, Messenger-rna, Liposomes, Mutation, Nanoparticles, RNA Interference, CX, 111204 Cancer Therapy (excl. Chemotherapy and Radiation Therapy)
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