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Media Farmasi Jurnal Ilmu Farmasi
Article . 2013 . Peer-reviewed
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Media Farmasi Jurnal Ilmu Farmasi
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MENINGKATKAN KERJA FUNGSI GINJAL DENGAN KONSUMSI TEPUNG GANYONG (Canna edulis Kerr.)

Authors: Grin Fariah; Endang Darmawan;

MENINGKATKAN KERJA FUNGSI GINJAL DENGAN KONSUMSI TEPUNG GANYONG (Canna edulis Kerr.)

Abstract

e"> Gout adalah peradangan akibat adanya endapan kristal asam urat pada sendi dan jari. Ganyong dengan kandungan karbohidrat yang tinggi dapat meningkatkan fungsi kerja ginjal yang diujikan pada tikus yang mengalami hiperurisemia dengan melakukan diet fiber. Hiperurisemia adalah keadaan di mana terjadi peningkatan asam urat di dalam darah darah. Tujuan dari penelitian ini adalah untuk mempelajari pengaruh konsumsi tepung ganyong pada tikus yang menderita penyakit gout terhadap fungsi ginjal. Penetapan kadar kreatinin plasma tikus menggunakan metode Jaffe ( Creatinine FS ). Perlakuan pemberian suspensi tepung ganyong tersebut dilakukan pada hari ke-1, 3,dan 7. Data kadar kreatinin rata-rata antar kelompok perlakuan dianalisis secara statistik menggunakan uji Kruskall-Wallis (non parametrik) dan dilanjutkan dengan uji Mann Whitney (p<0,05). Hasil penelitian menunjukkan bahwa pemberian tepung ganyong selama 7 hari dapat menurunkan kadar kreatinin rata-rata pada tikus yang diinduksi dengan kalium oksonat (p<0,05). Hal ini ditunjukan oleh nilai AUC kelompok pemberian tepung ganyong dosis 0,75; 1,5; 2,5 g/kgBB (p.o.) adalah secara Secara keseluruhan dapat disimpulkan bahwa pemberian tepung ganyong selama 7 hari dapat menurunkan kadar kreatinin plasma tikus yang diinduksi dengan kalium oksonat, lebih lanjut dapat memperbaiki fungsi kerja ginjal. Kata kunci : ganyong ( Canna edulis Kerr.), gout, hiperurisemia, kreatinin. berturut-turut sebesar 26,67 ± 3,96, 28,10 ± 4,80, dan 23,41 ± 4,84 (p<0,05),

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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