Infectivity of Porcine Circovirus 1 and Circovirus 2 in Primary Porcine Hepatocyte and Kidney Cell Cultures
Copyright policy )Infectivity of Porcine Circovirus 1 and Circovirus 2 in Primary Porcine Hepatocyte and Kidney Cell Cultures
Infectivity of porcine circovirus (PCV) 1 and PCV2 was examined in primary porcine hepatocyte culture by comparing that of PCV in primary kidney cell culture. The virus titer of PCV2-infected hepatocyte cultures was higher than that of the PCV1-infected hepatocyte cultures and the PCV-infected kidney cell cultures. The number of virus-positive cells was most abundant in PCV2-infected hepatocyte cultures as determined by immunohistochemistry and/or in situ hybridization. The results of our data suggest that PCV2 preferably infects cultured hepatocytes as observed in the liver of pigs with postweaning multisystemic wasting syndrome.
Circovirus, Male, Swine Diseases, infectivity, Swine, Wasting Syndrome, Liver Diseases, porcine circovirus, primary porcine hepatocyte cultures, Kidney, Immunohistochemistry, Specific Pathogen-Free Organisms, Animals, Newborn, Hepatocytes, Animals, Swine, Miniature, Circoviridae Infections, Antigens, Viral, Cells, Cultured
Circovirus, Male, Swine Diseases, infectivity, Swine, Wasting Syndrome, Liver Diseases, porcine circovirus, primary porcine hepatocyte cultures, Kidney, Immunohistochemistry, Specific Pathogen-Free Organisms, Animals, Newborn, Hepatocytes, Animals, Swine, Miniature, Circoviridae Infections, Antigens, Viral, Cells, Cultured
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