
Two strains of Bovine viral diarrhea virus 2 (BVDV-2) were isolated from calves in northern Italy. Variations in the 5'-untranslated region (UTR) of the genome were studied by primary structure alignment and neighbor-joining method based phylogenetic tree analyses and by palindromic nucleotide substitutions at the three variable loci in the 5'-UTR. Genetic analysis indicated their appurtenance to genovar BVDV-2a. Nucleotide sequence at the 5'-UTR of strain BS-95-II, one of the Italian isolates from healthy calves, showed 98% homology to that of the Japanese isolate OY89, a cytopathic strain derived from cattle with mucosal disease.
Bovine viral diarrhea virus 2; genovar; pestivirus, Diarrhea Viruses, Bovine Viral, General Veterinary, Base Sequence, Molecular Sequence Data, Sequence Homology, Nucleic Acid, DNA, Viral, Animals, Cluster Analysis, Nucleic Acid Conformation, Bovine Virus Diarrhea-Mucosal Disease, Cattle, 5' Untranslated Regions, Phylogeny
Bovine viral diarrhea virus 2; genovar; pestivirus, Diarrhea Viruses, Bovine Viral, General Veterinary, Base Sequence, Molecular Sequence Data, Sequence Homology, Nucleic Acid, DNA, Viral, Animals, Cluster Analysis, Nucleic Acid Conformation, Bovine Virus Diarrhea-Mucosal Disease, Cattle, 5' Untranslated Regions, Phylogeny
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