Background: The palate is defined as the roof of the mouth. It is alienated into soft palate which is essential for nasal passage protection and formation of speech sound and the bony hard palate which acts as a barrier between the mouth and the nasal cavity. A natural opening in the palate for nerves and blood vessels can create a passage for neoplasms to spread into the nasal cavity such as epidermoid carcinoma, adenocarcinoma and benign mixed tumors and rarely Melanoma, lymphosarcoma and Myosarcoma. Neoplasms of the palates results in significant masticatory, speech and swallowing disturbance and surgery remains the recommended treatment modality. However, provided the profound functional and cosmetic importance of the oral cavity, management of Palates cancers requires a thorough understanding of disease progression, approaches to management and options for reconstruction. Aim of the study: wasto review the different types of neoplasms of the Palates along with the etiology, diagnosis and with emphasis on the surgical intervention. Methods: electronic search of available Literature review in the scientific database of retrospective studies and systematic reviews investigating incidence, prevalence, etiology, symptoms, risk factors, diagnosis and surgical intervention of different types of oral cavity particularly palatal neoplasm from 1960 to 2017– (Medline, Embase, the Cochrane Library , NHS center websites as well as an individual Dentistry journals such as International Journal of Prosthodontics, International Journal of Periodontics and Restorative Dentistry. Search included English Publications which were obtained from both reprint requests and by searching the database. Conclusion: Cancer of the oral cavity is mostly trigger by smoking, alcohol abuse. The most common neoplasms of the hard palate are MSGTs and SCCs for the soft palate. Primary surgical resection with or without postoperative adjuvant therapy remains the upmost recommended treatment approach. It is also critical to have a Multidisciplinary treatment to help improve the oncologic and functional results in oral cancer patients.