On the algorithm of code obfuscation, opaque predicate is used to confuse the judgment of the program branches to achieve complex control flow statement. Currently, there are problems o f obfuscation on the opaque predicate. The first problem is the isolation. the relation between opaque predicate is relatively isolated, onc e an opaque predicates Boolean value is obtained, the branch flow will always be identified; Second is the reversible, an attacke r can determine the opaque predicate the Boolean value by analyzing reversible slicing attacks. In this paper, we proposed multi-poin t function opaque predicate obfuscation algorithm, using multi-function features makes opaque predicates interdependent and avoid reversible slicing attacks. Experimental data demonstrates that the obfuscated program performance and security has been significantly improved.