The article describes the history, effects and application areas of combined laseropforesis and elec-tromyostimulation methods. The inclusion of physical factors into complex therapeutic measures is quite important in a view of complications of isolated drug therapy. Laseropforesis and electromyostimulation are used in treatment of many pathologies in different areas of medicine. Therapeutic effect is realized by the injected drugs and by laser radiation itself. Application of methods does not only eliminate the major symptoms, but also improves microcirculation in the affected area, and throughout the body. This leads to general improvement of the functional systems of the body and contributes to the formation of different adaptation mechanisms.