
doi: 10.1271/bbb.70065
pmid: 17690448
A new caffeic acid cinnamyl ester (1) was isolated from the n-hexane-soluble fraction of an MeOH extract of the gum resin of Ferula assa-foetida L. The structure was determined to be (2E)-3,4-dimethoxycinnamyl-3-(3,4 diacetoxyphenyl) acrylate on the basis of spectroscopic data including 1D- and 2D-NMR. Compound 1 showed moderate activity for inhibiting LPS-induced nitric oxide production in murine macrophage RAW264.7 cells, with an IC50 value of 54.9 microm.
Magnetic Resonance Spectroscopy, Molecular Structure, Umbelliferae, resin, Esters, caffeic acid cinnamyl ester, <I>Ferula assa-foetida</I> L., Ferula
Magnetic Resonance Spectroscopy, Molecular Structure, Umbelliferae, resin, Esters, caffeic acid cinnamyl ester, <I>Ferula assa-foetida</I> L., Ferula
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 18 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
