Mac1 Positive Cells Are Required for Enhancement of Splenocytes Proliferation Caused by Bisphenol A
Copyright policy )Mac1 Positive Cells Are Required for Enhancement of Splenocytes Proliferation Caused by Bisphenol A
We examined the effects of bisphenol A (BPA) on immune cells and it was shown that BPA upregulated the proliferation of murine splenocytes stimulated with Concanavalin A (ConA). The upregulating effects of BPA were removed with depleting Mac1+ cells from the splenocytes. This study provides evidence for the first time that Mac1+ cells were required for enhancement of splenocytes proliferation caused by bisphenol A.
- Food Research Institute Japan
Mice, Inbred BALB C, Dose-Response Relationship, Drug, T-Lymphocytes, Macrophage-1 Antigen, Mice, Phenols, Concanavalin A, Animals, Thy-1 Antigens, Female, Bisphenol A Compounds, Benzhydryl Compounds, Cell Division, Cells, Cultured, Spleen
Mice, Inbred BALB C, Dose-Response Relationship, Drug, T-Lymphocytes, Macrophage-1 Antigen, Mice, Phenols, Concanavalin A, Animals, Thy-1 Antigens, Female, Bisphenol A Compounds, Benzhydryl Compounds, Cell Division, Cells, Cultured, Spleen
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