Acivicin Induce Filamentous Growth ofSaccharomyces cerevisiae
Copyright policy )Acivicin Induce Filamentous Growth ofSaccharomyces cerevisiae
The antibiotic acivicin is a known inhibitor of gamma-glutamyl transpeptidase (gammaGTP). We found that acivicin can induce filamentous growth in both diploid and haploid cells of Saccharomyces cerevisiae. This phenomenon is not related to the inhibition of gammaGTP or interference in glutathione metabolism. Interestingly, yeasts used in the brewing industry are more sensitive to acivicin, suggesting that this dimorphological differentiation may be related to some characteristics of these particular strains.
Dose-Response Relationship, Drug, industrial strain, Isoxazoles, Saccharomyces cerevisiae, gamma-Glutamyltransferase, yeast, filamentous growth, Cell Division, acivicin
Dose-Response Relationship, Drug, industrial strain, Isoxazoles, Saccharomyces cerevisiae, gamma-Glutamyltransferase, yeast, filamentous growth, Cell Division, acivicin
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