
doi: 10.1271/bbb.65.1897
pmid: 11577739
Lincomycin (1), a glycosidic antibiotic, active against Gram-positive bacteria, was modified enzymatically with the aim of improving its physico-chemical and biological properties. Compound 1 was glycosylated using jack bean alpha-mannosidase to produce 7-O-alpha-D-mannopyranosyl-lincomycin (2).
Spectrometry, Mass, Electrospray Ionization, Glycosylation, Magnetic Resonance Spectroscopy, Chemical Phenomena, Chemistry, Physical, Fabaceae, Anti-Bacterial Agents, Lincomycin, Aminoglycosides, Aspergillus, alpha-Mannosidase, Mannosidases, Mannose
Spectrometry, Mass, Electrospray Ionization, Glycosylation, Magnetic Resonance Spectroscopy, Chemical Phenomena, Chemistry, Physical, Fabaceae, Anti-Bacterial Agents, Lincomycin, Aminoglycosides, Aspergillus, alpha-Mannosidase, Mannosidases, Mannose
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