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Bioscience Biotechnology and Biochemistry
Article . 2001 . Peer-reviewed
Full-Text: http://www.jstage.jst.go.jp/article/bbb/65/5/65_5_1211/_pdf
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Bioscience Biotechnology and Biochemistry
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Bioscience Biotechnology and Biochemistry
Article . 2001 . Peer-reviewed
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Bioscience Biotechnology and Biochemistry
Article . 2001
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https://dx.doi.org/10.1271/bbb...
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Glycitein Effect on Suppressing the Proliferation and Stimulating the Differentiation of Osteoblastic MC3T3-E1 Cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2001 English Publisher:Oxford University Press (OUP)Journal:Bioscience, Biotechnology, and Biochemistry, volume 65, pages 1,211-1,213 (issn: 0916-8451, eissn: 1347-6947, Copyright policy )
Authors: YOSHIDA, Hiroyuki; TERAMOTO, Takanori; IKEDA, Katsumi; YAMORI, Yukio;

doi: 10.1271/bbb.65.1211

pmid: 11440142

Glycitein Effect on Suppressing the Proliferation and Stimulating the Differentiation of Osteoblastic MC3T3-E1 Cells

Abstract

Glycitein, as one of the three major isoflavones in soybeans, directly but significantly (about 5%) suppressed the proliferation of MC3T3-E1 and stimulated bone-related protein (alkaline phosphatase (ALP) and osteocalcin (OC)) expression. These results indicate that glycitein suppresses the proliferation of osteoblasts and promotes differentiation from its progenitor.

Related Organizations
Keywords

Osteoblasts, Osteocalcin, osteocalcin, Cell Differentiation, 3T3 Cells, Alkaline Phosphatase, Isoflavones, Mice, Animals, glycitein, alkaline phosphatase, Cell Division, isoflavone

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 28
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
28
Top 10%
Top 10%
Average
bronze