Novel DPPH Radical Scavengers, Bisorbicillinol and Demethyltrichodimerol, from a Fungus
Copyright policy )Novel DPPH Radical Scavengers, Bisorbicillinol and Demethyltrichodimerol, from a Fungus
In our screening program for antioxidants with DPPH radical scavenging activity, we isolated four yellowish compounds from the fermentation broth of Trichoderma sp. USF-2690 strain isolated from a soil sample: two were novel compounds designated bisorbicillinol (1) and demethyltrichodimerol (2), and two were known compounds bisvertinolone (3) and trichodimerol (4). The structures of 1 and 2 were elucidated by spectroscopic evidence and chemical modification. Two compounds seemed to be the oxidized dimers of sorbicillin. In the evaluation of DPPH radical scavenging activity, bisorbicillinol gave the lowest ED50 value (31.4 μM) among the four compounds, equal to that of BHT (27.0 μM).
- University of Shizuoka Japan
- University of Shizuoka Japan
antioxidant, bisorbicillinol, DPPH radical scavenging compound, <i>Trichoderma</i> sp. USF-2690, demethyltrichodimerol
antioxidant, bisorbicillinol, DPPH radical scavenging compound, <i>Trichoderma</i> sp. USF-2690, demethyltrichodimerol
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).232 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 1% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 1% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!