Essential Cys-Pro-Cys Motif ofCaenorhabditis elegansCopper Transport ATPase
Copyright policy )Essential Cys-Pro-Cys Motif ofCaenorhabditis elegansCopper Transport ATPase
Caenorhabditis elegans putative copper ATPase (CUA-1) had been functionally expressed in a yeast delta ccc2 mutant (copper ATPase gene disruptant). We found that CUA-1 with Cys-Pro-Cys to Cys-Pro-Ala mutation could not rescue the yeast delta ccc2 mutant, suggesting that the carboxyl terminal cysteine residue in the conserved Cys-Pro-Cys motif is essential for copper transport.
- Osaka University Japan
Adenosine Triphosphatases, Sequence Homology, Amino Acid, Molecular Sequence Data, Biological Transport, Saccharomyces cerevisiae, Mutation, Animals, Amino Acid Sequence, Caenorhabditis elegans, Oligopeptides, Copper
Adenosine Triphosphatases, Sequence Homology, Amino Acid, Molecular Sequence Data, Biological Transport, Saccharomyces cerevisiae, Mutation, Animals, Amino Acid Sequence, Caenorhabditis elegans, Oligopeptides, Copper
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