Biological Activity of Purpurogallin
Copyright policy )Biological Activity of Purpurogallin
Purpurogallin showed antibacterial activity toward gram-positive bacteria. Strong activity against methicillin-resistant Staphylococcus aureus [minimal inhibitory concentration (MIC) against methicillin of 1600 micrograms/ml] was found, with MIC of 11.0 micrograms/ml. Purpurogallin inhibited the growth of all tested plants and decreased the chlorophyll content in the cotyledons of Brassica campestris subsp. rapa. It showed potent inhibitory activity against prolyl endopeptidase (the 50% inhibitory concentration was 1.6 x 10(-5) M), unlike its analogues, hinokitiol and tropolone.
Serine Proteinase Inhibitors, Molecular Structure, Serine Endopeptidases, Brassica, Microbial Sensitivity Tests, Gram-Positive Bacteria, Tropolone, Anti-Bacterial Agents, Benzocycloheptenes, Gram-Negative Bacteria, Monoterpenes, Prolyl Oligopeptidases
Serine Proteinase Inhibitors, Molecular Structure, Serine Endopeptidases, Brassica, Microbial Sensitivity Tests, Gram-Positive Bacteria, Tropolone, Anti-Bacterial Agents, Benzocycloheptenes, Gram-Negative Bacteria, Monoterpenes, Prolyl Oligopeptidases
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