Antimutagenic Activity of Caffeic Acid and Related Compounds

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1996 English Publisher:Informa UK LimitedJournal:Bioscience, Biotechnology, and Biochemistry, volume 60, pages 328-329 (issn: 0916-8451, eissn: 1347-6947,

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Authors: YAMADA, Jiro; TOMITA, Yoshifumi;

doi: 10.1271/bbb.60.328

pmid: 9063983

Antimutagenic Activity of Caffeic Acid and Related Compounds

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Abstract

Effects of caffeic acid and chlorogenic acid on mutagenicity were studied using the Salmonella typhimurium system. These compounds had inhibitory effects on the mutagenicity of Trp-P-1 and Glu-P-2. Caffeic acid completely eliminated the mutagenicity induced by activated Glu-P-2. Some compounds analogous to caffeic acid, such as cinnamic acid, coumaric acid, and ferulic acid, also significantly decreased the mutagenicity of Glu-P-2.

Related Organizations

University of Miyazaki
Japan
Yamaguchi University
Japan

Keywords

Caffeic Acids, related compounds analogous to caffeic acid, Mutagenicity Tests, chlorogenic acid, Antimutagenic Agents, antimutagenic activity, Chlorogenic Acid, caffeic acid, Mutagens

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