Neuroprotective Kaurane Diterpenes fromFritillaria ebeiensis
Copyright policy )Neuroprotective Kaurane Diterpenes fromFritillaria ebeiensis
The new kaurane diterpene, ent-3β-butanoyloxykaur-15-en-17-ol, and four known kaurane diterpenes were isolated from the bulbs of Fritillaria ebeiensis. Their structures were elucidated on the basis of extensive spectroscopic analyses (IR, ESI-MS, HR-ESI-MS, 1-D and 2-D NMR). All the isolates showed neuroprotective effects against MPP(+)-induced neuronal cell death in human dopaminergic neuroblastoma SH-SY5Y cells.
- Tohoku University Japan
- Nankai University China (People's Republic of)
- SVP College of Pharmacy India
Magnetic Resonance Spectroscopy, Molecular Structure, kaurane, Cell Survival, Spectrum Analysis, Molecular Conformation, Plant Roots, neuroprotective effect, Neuroblastoma, Neuroprotective Agents, Fritillaria, <I>Fritillaria ebeiensis</I>, Cell Line, Tumor, dietrpenoids, Humans, Diterpenes, Kaurane
Magnetic Resonance Spectroscopy, Molecular Structure, kaurane, Cell Survival, Spectrum Analysis, Molecular Conformation, Plant Roots, neuroprotective effect, Neuroblastoma, Neuroprotective Agents, Fritillaria, <I>Fritillaria ebeiensis</I>, Cell Line, Tumor, dietrpenoids, Humans, Diterpenes, Kaurane
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