Neuroprotective Kaurane Diterpenes fromFritillaria ebeiensis
Copyright policy )Neuroprotective Kaurane Diterpenes fromFritillaria ebeiensis
The new kaurane diterpene, ent-3β-butanoyloxykaur-15-en-17-ol, and four known kaurane diterpenes were isolated from the bulbs of Fritillaria ebeiensis. Their structures were elucidated on the basis of extensive spectroscopic analyses (IR, ESI-MS, HR-ESI-MS, 1-D and 2-D NMR). All the isolates showed neuroprotective effects against MPP(+)-induced neuronal cell death in human dopaminergic neuroblastoma SH-SY5Y cells.
- Nankai University China (People's Republic of)
- Tohoku University Japan
Magnetic Resonance Spectroscopy, Molecular Structure, Cell Survival, Spectrum Analysis, Molecular Conformation, Plant Roots, Neuroblastoma, Neuroprotective Agents, Fritillaria, Cell Line, Tumor, Humans, Diterpenes, Kaurane
Magnetic Resonance Spectroscopy, Molecular Structure, Cell Survival, Spectrum Analysis, Molecular Conformation, Plant Roots, Neuroblastoma, Neuroprotective Agents, Fritillaria, Cell Line, Tumor, Humans, Diterpenes, Kaurane
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