
doi: 10.1267/ahc.22.105
PCNA/cyclin was originally described in proliferating mammalian cells as a nuclear protein with an apparent molecular weight of 33, 000-36, 000, and recently found to be a DNA polymerase-delta auxiliary protein. When the cDNA for PCNA/cyclin was cloned and analyzed, it was found that the protein consisted of 261 amino acids with a calculated molecular weight of 28, 700 and the amino acid sequence was well conserved during evolution both in animal and plant kingdoms. The highly homologous nature of PCNA/cyclin suggests that the protein plays an essential role in DNA replication in eukaryotes.
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 19 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
