Biotransformation of β-amyrin acetate by Rhodobacter sphaeroides

descriptionPublicationkeyboard_double_arrow_right Article 01 May 2008 English Publisher:Elsevier BVJournal:Journal of Bioscience and Bioengineering, volume 105, pages 558-561 (issn: 1389-1723,

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Authors: Guan-E, Yang; Zhaoming, Zhang; Hongjun, Bai; Jun, Gong; Yufen, Wang; Baozhen, Li; Jiankuan, Li;

doi: 10.1263/jbb.105.558

pmid: 18558349

Biotransformation of β-amyrin acetate by Rhodobacter sphaeroides

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Abstract

The microbial transformation of beta-amyrin acetate (compound 1) occurred in the culture of Rhodobacter sphaeroides producing three metabolites. The metabolites were purified and identified as beta-amyrin (compound 2), (3beta)-olean-12-ene-3, 23-diol (compound 3), and erythrodiol (compound 4). Initially, it was found that beta-amyrin acetate could be deacetylated and hydroxylated by microbial methods.

Related Organizations

Shanxi Medical University
China (People's Republic of)
Shanxi University
China (People's Republic of)

Keywords

Bioreactors, Cell Culture Techniques, Rhodobacter sphaeroides, Oleanolic Acid, Biotransformation

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