
doi: 10.1248/cpb.58.662
pmid: 20460793
Three new 12-hydroxybriarane diterpenoids, excavatoids L-N (1-3), have been isolated from the cultured octocoral Briareum excavatum. The structures of new briaranes 1-3 were elucidated by the interpretations of spectroscopic methods. Excavatoid L (1) displayed moderate inhibitory effects on superoxide anion generation and elastase release by human neutrophils.
Biological Products, Magnetic Resonance Spectroscopy, Molecular Structure, Pancreatic Elastase, Neutrophils, Anthozoa, Gene Expression Regulation, Superoxides, Animals, Humans, Diterpenes
Biological Products, Magnetic Resonance Spectroscopy, Molecular Structure, Pancreatic Elastase, Neutrophils, Anthozoa, Gene Expression Regulation, Superoxides, Animals, Humans, Diterpenes
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