
doi: 10.1248/cpb.56.730
pmid: 18451569
Two new bicyclic hexapeptides, RA-XXIII and RA-XXIV, were isolated from the roots of Rubia cordifolia L. (Rubiaceae). Their structures were determined by the analysis of their 2D NMR spectra, chemical methods, and X-ray crystallography. The IC50 values of RA-XXIII and RA-XXIV against P-388 leukemia cells were 0.16 and 0.48 microg/ml, respectively.
Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Spectrophotometry, Infrared, RA-XXIII, Rubia, <i>Rubia cordifolia</i>, Bromine, Crystallography, X-Ray, Antineoplastic Agents, Phytogenic, Methylation, Peptides, Cyclic, Plant Roots, peptide, Ammonia, cytotoxicity, Spectrophotometry, Ultraviolet, RA-XXIV, X-ray crystallography
Spectrometry, Mass, Electrospray Ionization, Magnetic Resonance Spectroscopy, Spectrophotometry, Infrared, RA-XXIII, Rubia, <i>Rubia cordifolia</i>, Bromine, Crystallography, X-Ray, Antineoplastic Agents, Phytogenic, Methylation, Peptides, Cyclic, Plant Roots, peptide, Ammonia, cytotoxicity, Spectrophotometry, Ultraviolet, RA-XXIV, X-ray crystallography
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 31 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Top 10% |
