New Withanolide Glycosides from Physalis peruviana L.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1999 English Publisher:Pharmaceutical Society of JapanJournal:Chemical and Pharmaceutical Bulletin, volume 47, pages 477-480 (issn: 0009-2363, eissn: 1347-5223,

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Authors: Saeed AHMAD; Rehana YASMIN; Abdul MALIK;

doi: 10.1248/cpb.47.477

New Withanolide Glycosides from Physalis peruviana L.

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Abstract

Four new withanolide glycosides (1-4) have been isolated from Physalis peruviana. Their structures were established as (20R,22R)-1α-acetoxy-14α,20-dihydroxywitha-5,24-dienolide-3β-(O-β-D-glucopyranoside) (1), (20S,22R)-1α-acetoxy-27-hydroxywitha-5,24-dienolide-3β-(O-β-D-glucopyranoside) (2), (20R,22R)-20,27-dihydroxy-1-oxowitha-5,24-dienolide-3β-(O-β-D-glucopyranoside) (3), and (20R,22R)-14α,20,27-trihydroxy-1-oxowitha-5,24-dienolide-5β-(O-β-D-glucopyranoside) (4) on the basis of spectroscopic data including two dimensional NMR techniques and through chemical transformations.

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University of Karachi
Pakistan

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