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Chemical and Pharmaceutical Bulletin
Article . 1998 . Peer-reviewed
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Chemical and Pharmaceutical Bulletin
Article . 1998 . Peer-reviewed
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Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin
Article . 1998
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https://dx.doi.org/10.1248/cpb...
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Characterization and Determination of Human Urinary Keratan Sulfate.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1998 English Publisher:Pharmaceutical Society of JapanJournal:Chemical and Pharmaceutical Bulletin, volume 46, pages 97-101 (issn: 0009-2363, eissn: 1347-5223, Copyright policy )
Authors: TOYODA, Hidenao; DEMACHI, Yoshikuni; KOMORIYA, Shizuyo; FURUYA, Nobuyoshi; TOIDA, Toshihiko; IMANARI, Toshio;

doi: 10.1248/cpb.46.97

pmid: 9468641

Characterization and Determination of Human Urinary Keratan Sulfate.

Abstract

Keratan sulfate was isolated from normal human urine and was characterized by sugar compositional analysis and H-NMR spectroscopy. It was found that KS from human urine is classified as skeletal type (KS-II type chain) with an O-glycosidic linkage between galactosamine and serine (or threonine). H-NMR studies revealed that urinary KS is not a proteoglycan but a polysaccharide (molecular weight is about 5 kDa). The quantitation of human urinary KS by HPLC showed that urinary KS is excreted at constant levels (0.07 +/- 0.015 microgram/mg creatinine).

Related Organizations
Keywords

Threonine, Magnetic Resonance Spectroscopy, keratan sulfate, Carbohydrates, keratanase, Galactosamine, Molecular Weight, human urine, Keratan Sulfate, Polysaccharides, ^1H-NMR, Serine, Humans, Electrophoresis, Polyacrylamide Gel, HPLC, Chromatography, High Pressure Liquid

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Average
Top 10%
Average
gold