
doi: 10.1248/cpb.13.7
pmid: 5864288
Uridine-5-carboxaldehyde (I), uridien-5-carboxylic acid (II), and 1-(β-D-ribofuranosyluronic acid) uracil-5-carboxaldehyde (III) were isolated and characterized form the reaction products obtained after catalytic oxidation of uridine-5-methanol (IV). Five aldehyde hydrazone derivatives of I and III were synthesized. Catalytic oxidation of several pyrimidine nucleosides gave the corresponding uronic acid derivatives. The ease of the oxidation of these compounds was found different, depending upon the base moieties.
Aldehydes, Pyridines, Chemistry, Pharmaceutical, Antineoplastic Agents, Nucleosides
Aldehydes, Pyridines, Chemistry, Pharmaceutical, Antineoplastic Agents, Nucleosides
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