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Biological and Pharmaceutical Bulletin
Article . 1995 . Peer-reviewed
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Biological and Pharmaceutical Bulletin
Article . 1995 . Peer-reviewed
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Biological and Pharmaceutical Bulletin
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Biological and Pharmaceutical Bulletin
Article . 1996
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Mutagenicity of Alkyl Azides.

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1995 English Publisher:Pharmaceutical Society of JapanJournal:Biological and Pharmaceutical Bulletin, volume 18, pages 1,805-1,807 (issn: 0918-6158, eissn: 1347-5215, Copyright policy )
Authors: MATSUMURA, Yasufumi; SHIOZAWA, Tatsushi; MATSUSHITA, Hidetsuru; TERAO, Yoshiyasu;

doi: 10.1248/bpb.18.1805

pmid: 8787815

Mutagenicity of Alkyl Azides.

Abstract

Alkyl azides showed mutagenicity for S. typhimurium TA100 strain with S9 mix. However, no significant activity was observed for TA98 either with or without S9 mix or for TA100 without S9 mix. On the other hand, 3-azido-1,2-propanediol showed the enantioselective activity regardless of S9 mix. Two aryl azides tested were not mutagenic, and trimethylsilyl azide exhibited potent activity for TA100. Their structure-activity relationships are discussed.

Related Organizations
Keywords

Salmonella typhimurium, Azides, Structure-Activity Relationship, steroselectivity, Mutagenicity Tests, alkyl azide, S. typhimurium, mutagenicity

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    popularity
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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Average
Average
Average
gold